When a character is created, he or she is dealt two random personal quest cards and chooses one to keep, returning the other to the personal quest deck.

When a personal quest is complete, that character must retire (on their next visit to Gloomhaven).

A character’s personal quest is their primary reason for participating in a party.

Fulfilling personal quests will always unlock new content for the game. They will allow the player to open a sealed box or envelope,

Personal quests usually unlock a new character class. Unlocked character classes are available for anyone starting a new character.

Any time players are directed to open a box or envelope and it has already been opened because of some previous condition, a new random item design and random side scenario are unlocked instead.

It is possible to run out of available personal quest cards. If there are no personal quest cards left when a player creates a new character, then that character does not receive a personal quest.

A character without a personal quest can never retire, though the player is still free to switch characters whenever he or she wishes.