When a card leaves your hand, that action can activate only one power. For example, if you have a character power that says “discard a card to bless your check” and another power that says “discard a card to add the Fire trait to your check,” you can’t discard one card to activate both powers. Similarly, if you have a character power that says “discard a weapon to add a die to your check,” and a card in your hand that says “discard a weapon and this card to add a die to your check,” you can’t discard one weapon to satisfy both requirements.