You win if you acquire all 8 Crystals.
The Hibernating Beast wins if, at the end of your turn, any one Bacteria tile has reached the 4th level, or if 5 Immune Response cards are in play, as in the game for 2 players.
If, during the Beast’s turn, the Stomach deck runs out and the Tract can not be filled, the game ends immediately. Scoring is carried out in the same way as in Ending Number Two of the game for 2 players.