When a Hero character card is reduced to 0 HP or would be otherwise destroyed, flip that character card and remove all of their non-character cards from the game. Incapacitated Heroes no longer have PLAY, POWER, or DRAW Phases, nor can they play cards, use powers, or draw cards. They have no HP value, thus they are not targets, nor can they regain HP.
On an incapacitated Hero's turn, they may use only one of their incapacitated abilities during their INCAPACITATED PHASE, which happens between their START PHASE and their END PHASE. Incapacitated abilities aid their fellow still-active Heroes, so if all the Heroes have been knocked out except for one, that remaining Hero is greatly bolstered by their fallen friends!